Philip F Stahel Selected Research

Complement C3-C5 Convertases (C3 Convertase)

5/2014	Deficiency of complement receptors CR2/CR1 in Cr2⁻/⁻ mice reduces the extent of secondary brain damage after closed head injury.
7/2012	The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria.
6/2006	Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Philip F Stahel Research Topics

Disease

20	Wounds and Injuries (Trauma) 10/2021 - 08/2002
15	Traumatic Brain Injuries (Traumatic Brain Injury) 10/2021 - 08/2002
9	Neuroinflammatory Diseases 05/2014 - 08/2002
8	Craniocerebral Trauma (Head Injury) 10/2021 - 09/2003
7	Hemorrhage 12/2019 - 10/2006
7	Closed Head Injuries 03/2016 - 08/2002
6	Infections 12/2019 - 03/2003
6	Inflammation (Inflammations) 01/2012 - 08/2002
5	Multiple Trauma (Multiple Injuries) 12/2017 - 10/2006
5	Open Fractures (Compound Fracture) 04/2016 - 07/2010
4	Surgical Wound Infection 12/2017 - 04/2010
4	Compartment Syndromes 01/2016 - 07/2010
3	Sepsis (Septicemia) 01/2012 - 01/2009
3	Shock 01/2012 - 01/2007
2	Ankle Fractures 10/2021 - 02/2015
2	Brain Injuries (Brain Injury) 10/2021 - 05/2014
2	COVID-19 01/2020 - 01/2020
2	Hemorrhagic Shock 12/2017 - 10/2006
2	Osteomyelitis 08/2015 - 03/2009
2	Spinal Cord Injuries (Spinal Cord Injury) 02/2015 - 12/2012
2	Gliosis 05/2014 - 04/2012
2	Pain (Aches) 05/2013 - 04/2013
2	Reperfusion Injury 01/2012 - 11/2011
2	Brain Edema (Cerebral Edema) 01/2009 - 08/2002
2	Central Nervous System Diseases (CNS Diseases) 05/2006 - 08/2002
2	Pancreatitis 03/2003 - 03/2003
1	Respiratory Insufficiency (Respiratory Failure) 01/2020
1	Fracture Dislocation 01/2017
1	Distal Femoral Fractures 01/2016
1	Ectopic Pregnancy 01/2016
1	Patella Fracture 06/2015
1	Thoracic Injuries (Chest Injury) 02/2015
1	Coma (Comas) 02/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2014
1	Tibial Plateau Fractures 07/2014
1	Adenocarcinoma 04/2014
1	Bone Fractures (Bone Fracture) 09/2013
1	Heterotopic Ossification (Ectopic Ossification) 04/2013
1	Cerebral Malaria 07/2012

Drug/Important Bio-Agent (IBA)

16	Complement System Proteins (Complement)IBA 10/2021 - 09/2003
7	CytokinesIBA 04/2012 - 08/2002
6	Anti-Bacterial Agents (Antibiotics)IBA 08/2015 - 03/2003
5	Proteins (Proteins, Gene)FDA Link 11/2014 - 08/2002
4	Biomarkers (Surrogate Marker)IBA 10/2021 - 05/2011
4	Interleukin-18 (Interleukin 18)IBA 03/2007 - 08/2002
3	Complement C3 (C3 Complement)IBA 03/2016 - 05/2011
3	Complement C3-C5 Convertases (C3 Convertase)IBA 05/2014 - 06/2006
3	ChemokinesIBA 01/2012 - 04/2005
2	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 10/2021 - 03/2010
2	Neuroprotective AgentsIBA 03/2016 - 08/2002
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2012 - 01/2008
2	CalciumIBA 01/2010 - 10/2006
2	InterleukinsIBA 03/2007 - 08/2002
2	Blood Coagulation Factors (Coagulation Factor)IBA 01/2007 - 10/2006
2	Complement Inactivating AgentsIBA 05/2006 - 09/2003
1	mesoglycanIBA 10/2021
1	remdesivirIBA 01/2020
1	Antiviral Agents (Antivirals)IBA 01/2020
1	SynucleinsIBA 11/2014
1	Immunoglobulin M (IgM)IBA 05/2014
1	Complement Receptors (Complement Receptor)IBA 05/2014
1	Complement 3d Receptors (Complement Receptor 2)IBA 05/2014
1	salicylhydroxamic acid (SHAM)IBA 02/2013
1	SteroidsIBA 12/2012
1	HMGB1 Protein (HMG1)IBA 09/2012
1	LigandsIBA 01/2012
1	AnaphylatoxinsIBA 01/2012
1	CorticosteroneIBA 12/2011
1	ElectrolytesIBA 12/2011
1	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2011
1	AldosteroneIBA 12/2011

Therapy/Procedure

6	Fracture Fixation 12/2019 - 05/2009
3	Resuscitation 12/2017 - 01/2007
2	Therapeutics 01/2020 - 08/2015
2	Surgical Amputation (Amputations) 04/2016 - 11/2008
2	Intramedullary Fracture Fixation 05/2013 - 03/2009
2	Reoperation 04/2013 - 02/2009
2	Blood Transfusion (Blood Transfusions) 04/2011 - 01/2009
1	Arthrodesis 10/2021
1	Extracorporeal Membrane Oxygenation 01/2020
1	Laparotomy 12/2017
1	Laminectomy 01/2017
1	Operative Surgical Procedures 01/2016
1	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2016
1	Gynecologic Surgical Procedures (Gynecologic Surgery) 01/2016
1	Salpingectomy 01/2016
1	Transjugular Intrahepatic Portasystemic Shunt 08/2015
1	Aftercare (After-Treatment) 06/2015
1	Tracheostomy 02/2015
1	Critical Care (Surgical Intensive Care) 02/2015
1	Artificial Respiration (Mechanical Ventilation) 02/2015
1	Operative Time 07/2014
1	Immunomodulation 05/2014
1	Antibiotic Prophylaxis 10/2013
1	Bone Transplantation (Bone Grafting) 09/2013
1	Catheters 08/2013
1	Surgical Instruments (Clip) 04/2013
1	Ligation 12/2011
1	Punctures 12/2011
1	Spinal Fusion (Spondylosyndesis) 10/2011